The team confirmed the news on its website and reported that the 23-year-old had tested positive for methylhexanamine. The substance, an active ingredient in nasal congestion medication, is listed on the banned lists of both the International Cycling Federation (UCI) and World Anti-Doping Agency (WADA).
The team said that an investigation would be carried out in accordance with UCI and WADA regulations, but that Vacansoleil and L'hotellerie had mutually agreed to terminate his contract.
It is the second time in as many years that L'hotellerie has been dismissed by a team. Last year, Skil-Shimano dissolved its contract with the rider after he failed to attend two appointments with the team.
L'hotellerie finished eleventh and won the climbing classification at Paris-Nice, in 2008.
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