The International Cycling Union (UCI) has tweaked the 2012 WorldTour calendar to avoid a clash with the road events at the London Olympic Games.
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| 1/17/2012 - 1/22/2012 | Tour Down Under |
| 3/4/2012 - 3/11/2012 | Paris - Nice |
| 3/7/2012 - 3/13/2012 | Tirreno-Adriatico |
| 3/17/2012 | Milano-Sanremo |
| 3/19/2012 - 3/25/2012 | Volta Ciclista a Catalunya |
| 3/23/2012 | E3 Prijs Vlaanderen - Harelbeke |
| 3/25/2012 | Gent - Wevelgem |
| 4/1/2012 | Ronde van Vlaanderen / Tour des Flandres |
| 4/2/2012 - 4/7/2012 | Vuelta Ciclista al Pais Vasco |
| 4/8/2012 | Paris - Roubaix |
| 4/15/2012 | Amstel Gold Race |
| 4/18/2012 | La Flèche Wallonne |
| 4/22/2012 | Liège - Bastogne - Liège |
| 4/24/2012 - 4/29/2012 | Tour de Romandie |
| 5/5/2012 - 5/27/2012 | Giro d'Italia |
| 6/3/2012 - 6/10/2012 | Critérium du Dauphiné |
| 6/9/2012 - 6/17/2012 | Tour de Suisse |
| 6/30/2012 - 7/22/2012 | Tour de France |
| 7/10/2012 - 7/16/2012 | Tour de Pologne |
| 8/6/2012 - 8/12/2012 | Eneco Tour |
| 8/14/2012 | Clasica Ciclista San Sebastian |
| 8/18/2012 - 9/9/2012 | Vuelta a España |
| 8/19/2012 | Vattenfall Cyclassics |
| 8/26/2012 | GP Ouest France - Plouay |
| 9/7/2012 | Grand Prix Cycliste de Québec |
| 9/9/2012 | Grand Prix Cycliste de Montréal |
| 10/10/2012 - 10/14/2012 | Tour of Beijing |
| 10/20/2012 | Il Lombardia |
